Central American rodent that has given its name to a grey flecked coat coloration in mice caused by alternate light and dark bands on individual hairs. The gene codes for a 131 residue secreted protein that regulates phaeomelanin synthesis in melanocytes but associated with the locus are genes important in embryonic development. Mice with dominant mutation at the Ay locus develop diabetes and obesity. The agouti gene product binds to melanocortin receptor 1 but does not antagonise a -MSH and has similar antiproliferative effects on melanoma cells in culture. The dark agouti (DA) rat has a high susceptibility to developing arthritis.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • agouti — [ aguti ] n. m. • 1758; agoutin 1556; var. acouti, acoutyXVII e; tupi guarani acouti ♦ Petit mammifère (rongeurs) des Antilles et de l Amérique du Sud, de la taille d un lièvre. ● agouti nom masculin (mot guarani) Petit rongeur d Amérique latine …   Encyclopédie Universelle

  • Agouti — refers to a number of species of rodents as well as a number of genes affecting coat coloration in several different animals.*When referring to a rodent, agouti can mean: ** The common agoutis (genus Dasyprocta ) are those popularly called… …   Wikipedia

  • Agouti — Saltar a navegación, búsqueda ? Pacas Rango fósil: Recent Agouti paca …   Wikipedia Español

  • Agouti — A*gou ti, Agouty A*gou ty ([.a]*g[=oo] t[i^]), n. [F. agouti, acouti, Sp. aguti, fr. native name.] (Zo[ o]l.) 1. A rodent of the genus {Dasyprocta}, about the size of a rabbit, peculiar to South America and the West Indies. The most common… …   The Collaborative International Dictionary of English

  • agouti — agouti. См. агути. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • agouti — n. pl. agouties [ə go͞ot′ē] n. agoutis [Fr (? via Sp agutí) < Tupí Guaraní akutí] a rabbit sized, nocturnal rodent (family Dasyproctidae) with grizzled fur, found in tropical America: also sp. agouty n. agouties …   English World dictionary

  • Agouti —  Pour l’article homonyme, voir gène agouti.  Nom vernaculaire ou nom normalisé ambigu : Le terme « Agouti » s applique en français à plusieurs taxons distincts …   Wikipédia en Français

  • Agouti — Wildfarbenes Kaninchen Schwarze Ratte …   Deutsch Wikipedia

  • agouti — Wildfarbenes Kaninchen Agouti Farbratte …   Deutsch Wikipedia

  • agouti — /euh gooh tee/, n., pl. agoutis, agouties. 1. any of several short haired, short eared, rabbitlike rodents of the genus Dasyprocta, of South and Central America and the West Indies, destructive to sugar cane. 2. an irregularly barred pattern of… …   Universalium

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”